CLEHR: Clinical from EHR
Graticule’s global eSourcing network connects sponsors to health system EHRs, unlocking real-world data at scale for clinical studies. Through secure standards-based interoperability, CLEHR eliminates manual EDC management and improves data sets for efficient, high impact research.
CLEHR: Clinical from EHR
Graticule’s global eSourcing network connects sponsors to health system EHRs, unlocking real-world data at scale for clinical studies. Through secure standards-based interoperability, CLEHR eliminates manual EDC management and improves data sets for efficient, high impact research.
The Challenges with Legacy Data Collection for Research
Sponsors require increasing amounts of patient data for trials through post approval follow-up to meet evidence and safety demands across competitive, regulated global markets. Yet data collection for research relies on outdated manual “cut-and-paste” workflows, where Clinical Research Coordinators transfer EHR data into CRFs in EDC systems.
Manual Data Entry and Source Data Verification (SDV) is inefficient
Use of EDC forms limits data for research
The concept of a digital RWD transfer from EHR to EDC systems has been around for years, but practical solutions have remained elusive to the industry. Barriers include a lack of a ready network of health system sites and the significant effort required to stand up sites on digital capabilities. CLEHR is different. CLEHR is eSourcing at scale.
Difference is CLEHR: Global Digital Network
CLEHR is a global digital network that connects leading IDNs and healthcare providers by integrating sponsors and sites through eSourcing that leverages USCDI open standards. How does CLEHR work? Through secure, de-identified digital transfer of EHR records, enhancing research data collection to improve operations efficiency and ensure data quality and accuracy.
- A secure honest broker cloud service, CLEHR seamlessly links site healthy system EHRs with sponsor IT systems, creating a powerful network that delivers on the promise of eSourcing at scale.
- Tapping the "toll free highway" of USCDI for data transfer provides access to EHRs without recurring EMR API costs.
The Benefit of CLEHR eSourcing:
Efficient data transfer: Reduces data entry to accelerate evidence generation. In recent use cases, 70% of the data transfer process is automated, with only 30% requiring manual effort for various legitimate reasons.
Eliminates Source Data Verification (SDV): Data acquired through CLEHR is accurate form the source, there is no need for SDV requests back to sites, effectively reducing SDV time to zero.
Data quality: Granular and relevant data offers a clear, accurate clinical picture of the patient and greater insight into trends.
Single-patient example of sourced vs. transcribed data
Data sourced directly from EHRs is more comprehensive than manually transcribed research data.
- 291 blood pressure measures with CLEHR. Only 2 blood pressure measures via manual EDC "cut and paste" by Clinical Research Coordinator.
- 360 tracked patient encounters with CLEHR. Only re-admission tracked via manual EDC "cut and paste" by Clinical Research Coordinator.
CLEHR for EHR to Sponsor Data Transfer at Scale
CLEHR-ly Making an Impact
Milestones highlight CLEHR’s role as a game-changer for efficient, high quality research studies.
- Rapid Site Activation: CLEHR has successfully integrated an adapter into the Epic Showcase, enabling sites to go live quickly—often in less than 4 weeks.
- Seamless Data Flow with 80+ Million Strong Global Patient Network Data is actively flowing into live studies from sites, with volumes surpassing expectations, ensuring timely and reliable data collection.
- Efficient Reuse: Sites are able to reuse their initial CLEHR connections for multiple studies, eliminating the need for new startup integrations for each study.
- Strong Vendor Partnerships: Contract Research Organizations (CROs) and EDC tool vendors are now partnering with CLEHR to accelerate access for their clients, further driving the adoption and efficiency of the platform.