Does SSRI use reduce COVID-19 mortality? A Study of EHR data in N3C Enclave Using Targeted Learning for Causal Inference
This poster was created for the American Medical Informatics Association. Our research objectives include evaluating the feasibility of using TMLE in the N3C Enclave, evaluating the potential protective effect of SSRI use in a large national cohort of COVID-19 patients by comparing risk of mortality in chronic SSRI (sertraline, fluvoxamine, fluoxetine) vs. naive patients, and developing insights around disparate findings from previous research showing mixed efficacy of SSRI use in COVID-19 patients.